Treatment‐planning considerations for prostate implants with the new linear RadioCoil™ Pd103 brachytherapy source
نویسندگان
چکیده
Recently, various linear source models, for example, 103Pd RadioCoil, have been introduced to overcome the shortcomings of traditional "seed" type interstitial prostate brachytherapy implants, such as migration and clumping of the seeds. However, the existing prostate treatment-planning systems have not been updated to perform dose calculation for implants with linear sources greater than 1.0 cm in length. In these investigations, two new models are developed for 3D dose calculation for a prostate implant with linear brachytherapy sources using the commercially available treatment-planning systems. The proposed models are referred to as the linear-segmented source (LSS) model and the point-segmented source (PSS) model. The calculated dose distributions obtained by these models for a single linear source have been validated by their comparison with the Monte Carlo-simulated data. Moreover, these models were used to calculate the dose distributions for a multilinear source prostate implant, and the results were compared to "seed" type implants. The results of these investigations show that the LSS model better approximates the linear sources than the PSS model. Moreover, these models have shown a better approximation of the dose distribution from a linear source for 0.5 cm source segments as compared to 1.0 cm source segments. However, for the points close to the longitudinal axis of the source located outside the region bounded by the active length, both models show differences of approximately +/-15%. These deficiencies are attributed to the limitations of the TG43 formalism for elongated sources.
منابع مشابه
Determination of Dosimetric Characteristics of IrSeed 125I Brachytherapy Source
Introduction Low dose rate brachytherapy sources have been widely used for interstitial implants in tumor sites, particularly in prostate. Dosimetric characteristics of a new IrSeed 125I brachytherapy source have been determined using the LiF thermoluminescent dosimeter (TLD) chips. Materials and Methods Dose rate constant, radial dose function, and anisotropy function around the IrSeed 125I so...
متن کاملCylindrical coordinate‐based TG‐43U1 parameters for dose calculation around elongated brachytherapy sources
In 2001, the use of cylindrical coordinates was demonstrated to be more suitable than was the use of polar coordinates for accurate computer calculations during treatment planning for 192Ir intravascular brachytherapy sources. In the present work, we investigated the applicability of cylindrical coordinate-based TG-43U1 parameters for dosimetric evaluation and dose calculations for RadioCoil 10...
متن کاملHistorical review of interstitial prostate brachytherapy
In the recent years, interstitial brachytherapy implantation has become the treatment of choice for early stage prostate cancer patients. Treatment of prostate cancer with radiation is traced back to 1909. Originally this treatment modality was very crude and could not gain much popularity till 1982. Advancements in radioactive source designs, introduction of new low energy radioactive sources,...
متن کاملFeasibility of calibrating elongated brachytherapy sources using a well-type ionization chamber.
Recently, elongated brachytherapy sources (active length >1 cm) have become commercially available for interstitial prostate implants. These sources were introduced to improve the quality of brachytherapy procedures by eliminating the migration and seed bunching associated with loose seed-type implants. However, the inability to calibrate elongated brachytherapy sources with the Wide-Angle Free...
متن کاملTG‐43U1 parameterization of elongated RadioCoil P103d brachytherapy sources
Recently, to eliminate problems associated with seed type sources, RadioMed Corporation (Tyngsboro, MA) introduced RadioCoil 103Pd sources for interstitial prostate implants. The RadioCoil sources are available in integral lengths ranging from 1.0 cm to 6.0 cm. In this project, dosimetric characteristics of these sources were determined following the TG-43U1 recommendations, with consideration ...
متن کامل